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Definition :
Laparoscopic partial nephrectomy uses a minimally invasive
approach (laparoscopy) to perform exactly the same procedure
that is done in open partial nephrectomy. In any partial nephrectomy
(open or laparoscopic), the kidney cancer is removed with a small
amount of normal tissue around it. The normal tissue around the
cancer that is removed is known as the margin, and this tissue serves
to assure that no cancer is left in the body. The term "negative
margin" means that the entire kidney cancer has been removed
completely.
A "positive margin" means that some of the
kidney cancer may have been left on the kidney. The laparoscopic
approach to partial nephrectomy means that no large incisions are
required to perform the procedure. Instead of a large incision,
three or four 1/2 cm to 1 cm incisions (less than 1/2 inch) are
made. The spaces in the body are gently filled with gas to make
working space and a small camera is placed into the body through
one of the incisions. The other small incisions are used to place
working instruments, which can be used to perform the procedure.
The kidney cancer is then identified. Usually, the
kidney cancer can be readily seen using the small camera (laparoscope).
If the cancer is deep within the kidney, a laparoscopic ultrasound
device can be used to very precisely identify the size and location
of the kidney cancer. The laparoscopic ultrasound can even determine
the amount of blood flow to the kidney and to the cancer. Once the
kidney cancer is identified, the kidney's blood supply is temporarily
stopped. By stopping the blood to the kidney, the surgery can be
performed without significant bleeding. The cancer is then removed
with the margin of normal tissue.
Once the kidney cancer has been removed, the kidney
is repaired by closing the collecting system (plumbing within the
kidney) and then by closing the functioning kidney tissues. The
removal of the kidney cancer and the repair of the kidney should
be in as short a time as possible to prevent long-term damage to
kidney function.
Technique:
Laparoscopic
parital nephrectomy for kidney cancer is performed by a
Urologist (kidney surgeon) in an operating room. Prior to scheduling
the procedure, each patient should have an extensive consultation
with their Urologist regarding the nature of their kidney disease
as well as all of the available treatment options. This discussion
should review all the advantages and limitations of each surgical
and non-surgical approach.
Once you and your Urologist have decided on laparoscopic
partial nephrectomy, a date for surgery is chosen. Typically, a
patient goes to the hospital on the day of surgery. General anesthesia
(you are completely asleep) is required. The Procedure is then done
through three or four small incisions, which are either 1/2 a centimeter
or 1 cm in length (less than 1/4 to 1/2 and inch). The kidney is
then identified so that the kidney cancer can be found. Once the
target kidney cancer is identified, the renal artery (blood supply
to the kidney) is temporarily blocked. With the blood supply temporarily
interrupted, it is possible to completely remove the kidney cancer
with a small margin of normal tissue all the way around it. Once
the cancer is removed, stitches are used to close the kidneys
collecting system (plumbing system within the kidney that carries
urine), to stop all the bleeding sites, and to close the functioning
tissue that makes up the majority of the kidney. The repair of the
area of the kidney where the kidney cancer has been removed is known
as reconstruction of the kidney.
Once the kidney has been reconstructed, the blood
supply to the kidney is opened, and the kidney cancer is removed
from the body by extending one of the small incisions. While the
patient is still under anesthesia, the surgeon works with a pathologist
to assure that the entire cancer has been removed (a negative surgical
margin has been achieved). Once complete removal of the kidney cancer
has been confirmed, a small tube may be left in the area of the
surgery (drain) to remove any excess fluids that may collect in
the area.
Once the procedure is complete, the patient is transferred
to the recovery room for observation and then to a hospital room.
Typically, on the day of surgery, the patient can drink liquids,
walk around, and is relatively comfortable with limited pain. On
the day after surgery it is common to have a regular diet. If a
drain has been left in place, it is usually removed on the first
day after surgery. If everything has gone well, most people are
discharged home on the first or second day after surgery with limited
well-controlled pain, eating a regular diet, and feeling well. On
discharge, oral antibiotics and oral pain medications are typically
prescribed.
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Candidates:
There
are a number of important patient and tumor parameters that are
critical in deciding the type of treatment that is best for a small
renal mass. Considerations are numerous but include: the size and
general radiographic appearance of the mass, the local anatomy of
the mass, the overall age and health condition of the patient, overall
kidney function, the number of lesions in the kidney, patient personal
preference, etc. The decision on a proper strategy for the treatment
of kidney cancer is challenging and should be made by each patient
in conjunction with a Urologist who is experienced in managing kidney
cancer.
Laparoscopic partial nephrectomy is a very effective
procedure for the treatment of kidney cancers that are less than
4 cm (less than 1 3/4 inches). The procedure itself is technically
demanding. However, in the hands of an experienced laparoscopic
surgeon, the majority of small renal masses can be managed with
a laparoscopic partial nephrectomy. While there are no strict age
criteria, young and healthy patients with small renal masses are
excellent candidates for laparoscopic partial nephrectomy.
In the hands of a laparoscopic expert, the cancer
control (negative margin rates or complete removal of
cancer) are the same as with open partial nephrectomy. As such,
most patients who are candidates for open partial nephrectomy can
have their procedures done laparoscopically, and therefore benefit
from the advantages of a minimally invasive approach (less bleeding,
less pain and faster recovery).
Tumor location is somewhat important in deciding between
surgical options for kidney cancer. Patients with kidney cancers
located very close to the middle of the kidney may be better candidates
for open partial nephrectomy or radical nephrectomy.
Advantages / Disadvantages:
Laparoscopic partial nephrectomy has the advantages
intrinsic to any procedure in which the cancer is completely removed.
After the procedure, an experienced pathologist can carefully review
the kidney cancer that has been removed to confirm that all the
cancer cells have been extracted. Additionally, even though laparoscopic
partial nephrectomy is a relatively new procedure, it is identical
in nature to open partial nephrectomy in which long-term results
for cancer control have been excellent.
As laparoscopic partial nephrectomy, by definition,
uses a laparoscopic approach, patients get all the benefits of a
minimally invasive procedure. Blood loss is significantly less with
laparoscopic partial nephrectomy compared to open partial nephrectomy.
Pain is also significantly less with laparoscopic partial nephrectomy.
The decreased blood loss, pain, and trauma to the body also result
in faster overall recovery from the operation. With laparoscopic
partial nephrectomy, patients return to full activity in less than
half the time it takes to recover from open partial nephrectomy.
As laparoscopic partial nephrectomy is a very technically
challenging operation, it is not offered at many centers. A disadvantage
of the procedure is that only few doctors offer this procedure to
their patients.
Follow-up:
Pathology Results The tissue that is
removed during the laparroscopic partial nephrectomy is evaluated
on the day of surgery to determine that the kidney cancer has been
completely removed. This evaluation is done with a technique called
frozen section, which is useful for determination of
the adequacy of the surgery. However, the final pathology
is established approximately one week after surgery when the pathologist
has had the proper time to fix (preserve) the specimen,
prepare slides, and evaluate the tissue under the microscope. The
final pathology reveals the type of kidney cancer that
has been treated and also gives the final confirmation of a negative
margin (total removal of all of the kidney cancer). Your surgeon
will usually call you at home with these results approximately one
week after surgery.
Activity after surgery - While patients will
typically be able to do routine activities such as eating and taking
care of everyday needs, it is generally suggested that no heavy
lifting or vigorous activity be performed for four to six weeks
to allow the body to recover. While it is surgeon dependent, most
surgeons will suggest only light lifting (less than 10lbs), gentle
activity, and no driving for one to two weeks after surgery. It
is typical for patients to feel drained or lack energy for several
weeks after surgery, and complete and full return to activity will
usually take four to six weeks. However, every patient is different
and recovery is somewhat variable. Generally, the patient will feel
better day by day.
Wound care and bandages - With laparoscopy,
wound care is generally very easy. The dressings (bandages) are
usually removed by the patient at home the second day after surgery.
Under the bandages there are small pieces of surgical tape. Once
these start to peel off on their own, the patient may remove them.
Removing the tape in the shower may be helpful and the adhesive
will soften and allow the tape to be removed gently and without
pain. Under the tape are the small wounds. The stiches are below
the skin and do not have to be removed as they absorb by themselves.
Bathing - Swimming and bathing in a tub should
not be done for one week after surgery, but showering is usually
permitted any time after the second day after surgery. The shower
should be with regular soap and water. An effort should be made
not to allow the shower to directly hit the wounds for the first
several days. The wounds should be cleaned with a dry and clean
towel and left uncovered. A small amount of oozing is possible for
the first few days after surgery, and a clean gauze with surgical
tape can be used to keep clothing dry. However, if there is any
significant leakage from the wound or if the would should become
red, hot, tender, or swollen, you should contact your doctor immediately.
Follow-up visit Your doctor will typically
call with the biopsy results one week after the surgery has been
performed. A follow-up visit with the surgeon is usually scheduled
approximately four weeks after the procedure has been done. At the
follow-up visit wounds are checked and follow-up radiographic imaging
is scheduled. Typically, an MRI or CT scan is scheduled for six
months after the procedure has been performed. Depending on the
final pathology report, which establishes the type of cancer that
was removed, a future follow-up regimen is then established.
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